Vitamin MePA Testimonials
by Gerald Aardsma; November 2, 2017
I reported in Aging: Cause and Cure (see the link to the book in the banner bar above) that both Helen and I experienced significant sleep benefits from taking vitamin MePA. Our experiences now appear to have been corroborated by others.
I summarized our experiences briefly on page 117 of Aging: Cause and Cure.
Once I had begun to take MePA, I also found that I was sleeping better. It is easiest to describe the change simply as a return to a more youthful sleep experience. Sleep was deeper and less interrupted. I needed less sleep, and I felt more rested.
Helen began taking 1 microgram MePA/day after I had been taking it for a year with no adverse side effects. ...
Three weeks later she began reporting greatly improved sleep.
Previously, she had been experiencing chronic sleep trouble.
A typical morning had begun with, "I slept so terribly again last night, I don't know how I can keep up, feeling like this..."
Now she was saying, "I haven't slept like this in years." Our grown children now comment on her remarkably improved ability to cope with life when they come home to visit.
She replies, "Yes, what a difference a good night's sleep makes!"
Over the past few months, a few volunteers have begun testing vitamin MePA. The purpose of these tests has been to gather more data on specific effects of the vitamin on overall health. The impact of the vitamin on sleep was of particular interest. The question I wished to answer was whether my experience and Helen's experience was reproducible with other vitamin MePA users.
To measure the effect of the vitamin on sleep, several participants were equipped with commercially available Fitbit Charge 2® bracelets. These devices automatically record activity and heart rate data, from which sleep stages are estimated on a daily basis. Two participants have sleep data which is helpful at the present time. (Several participants lost substantial early data due to difficulty syncing their Fitbit, others have not been in the trial long enough to expect to see any effect yet, and one, who works nights, has an atypical sleep routine with frequent naps, for which Fitbit is unable to estimate sleep stages.)
There are three stages of sleep: light, deep, and REM (rapid eye movement). These stages serve different functions, and their duration impacts how we feel and function the next day. For example, "When you wake up feeling refreshed in the morning, you're likely to have experienced solid periods of deep sleep during the previous night." (https://help.fitbit.com/articles/en_US/HELP_article/2163)
Participant #1 is a 59 year old female who was experiencing chronic sleep difficulties prior to taking Dr. Aardsma's Vitamin MePA Dietary Supplement. It is important to note that this participant is in heart failure and is taking a complex variety of medications for multiple health concerns.
Her sleep before beginning to take MePA was described as "inefficient, erratic, and unproductive." She described herself as "continually exhausted." Some nights she would be awake for multiple hours waiting to fall asleep.
The graph below shows data obtained from Participant #1's Fitbit. This particular graph shows the number of times she woke up each night. (We all wake up briefly many times each night, but most of these awake interludes are not remembered.) Note that the graph spans a little more than two months.
It is immediately obvious that there is quite a bit of scatter in the data. This is to be expected for several reasons. For one thing, the Fitbit cannot measure wakefulness directly. It can only measure motion and heart rate. It estimates wakefulness from these measurements. Then there is the question of the cause of any motion measured by the Fitbit. If you sleep with a spouse, for example, it is possible that some of the motion being detected is not being caused by you. In addition, sleep in general (including wakefulness at night) is impacted by many factors. For example, family or work stresses can induce insomnia, or one may have eaten something a little too strong, or one may have eaten a little too late in the evening. Such factors seem to exert an ever-increasing influence as we age, making it harder to get a good night's sleep. The individuals in this study are carrying on with their lives as normal and are subject to the ordinary ups and downs of life. This can be expected to translate into variability in sleep data from night to night.
The large scatter in the data precludes complex analyses and severely limits the degree of confidence which can be attached to conclusions drawn from the data. For this reason, I will restrict to a simple linear trendline analysis in what follows. We are, by its use, attempting to answer only the question, "Does vitamin MePA seem to be making this better or worse?"
In all of the graphs below, I have added a vertical red line to show when supplementation with vitamin MePA began. The trendline for the dataset, starting from the red line, is shown in black.
The trendline for the graph immediately below indicates improving sleep for Participant #1, with fewer times awake each night.
This is corroborated by the next graph, which shows the percentage of time the participant was awake each night. The trendline indicates that the participant is spending less of her total sleep time awake each night.
Finally, improved sleep is also corroborated by the next graph. The trendline indicates a slowly increasing percentage of REM plus deep sleep each night.
Because of the large amount of scatter in these data, the slopes of these trendlines cannot be regarded as certain, as mentioned above. For this reason, the participant's assessment of the effects of vitamin MePA on her sleep is of substantial value.
The participant reports that she has experienced significant difficulty getting to sleep only once since beginning to take the vitamin. She further reports that, about four weeks after beginning daily supplementation with the vitamin, she began to experience less "brain fog."
The biggest felt change has been with her ability to bounce back quickly after taxing events. Preparing for a holiday used to completely exhaust her for more than a week afterwards. She now can get a good night's sleep and be back to normal within a day or two. She describes herself as waking more rested and having better stamina throughout the day.
A close, independent observer reports:
My personal observation would be that she doesn't have the super lows in energy that she used to have. She still has rough days, but not to the same extreme. It was not unusual for days at a time to see her dragging her feet and going about the day with an extreme level of exhaustion. Even her speech would be slow and laborious. While doing simple household tasks like dishes or laundry, she would comment with great emphasis "I. Am So. Exhausted." (Her daughter says she would say this constantly.) She still says frequently that she is tired or worn out, but I haven't seen this level of complete exhaustion from her in quite some time.
These same three graphs, for the same period of time, are also all indicative of improved sleep for Participant #2.
Participant #2 is also a 59 year old female. She is in normal health for her age and she is without major health issues. She started taking Dr. Aardsma's Vitamin MePA Dietary Supplement only a month ago. She rates her sleep experience prior to starting on the vitamin as "poor." She reports that she is still waiting for this to change. She has slept better the past few nights, but notes that this may be due to being unusually exhausted as a result of an unusually high level of activity and an earlier, unusual sleep disturbance.
Anecdotal evidence continues to accumulate in support of the vitamin's positive impact on sleep. For example, my mother's testimonial included the observation, "I think I sleep sounder."
A recent set of observations by a medical professional in his early 50s seems especially significant. After two weeks on Dr. Aardsma's Vitamin MePA Dietary Supplement, he reports regarding himself:
This corroborates my own experience of needing less sleep and feeling more rested.
Have always slept well without problem; usually get 5-7 hours sleep. Now wake up after about 5 hours of sleep, ready for the day for past 5 days. Unable to get back to sleep. Feel rested and not unusually tired or sleepy throughout the day.
He goes on to report regarding his wife, also in her early 50s and also taking the vitamin for two weeks:
Sleeping more soundly for about 1 week. She noted she does not wake up when I leave for work. This is very unusual. She always was up to see me off. She has never been a sound sleeper.
The observation that Dr. Aardsma's Vitamin MePA Dietary Supplement improves some individuals' sleep experience appears to be robust. It appears that, as vitamin MePA deficiency disease progresses, loss of the normal, youthful sleep experience is one of many health casualties. Supplementation of the diet with MePA acts relatively quickly to begin to reverse this particular symptom of the disease.